Hyperbaric oxygen therapy and its mechanisms of action: implication of several molecular processes along with reactive species
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Treatment of nervous system injuries by hyperbaric oxygen: a review of molecular mechanisms
Background and aims: The use of hyperbaric oxygen therapy is one of the treatment methods to treat many diseases and injuries such as decompression sickness, wound healing, carbon monoxide poisoning, thermal burns, and nervous system injuries. This article aims to review the possible mechanisms of the effectiveness of this treatment in neurological injuries according to the available studies...
متن کاملProposed Mechanisms of Action of Selected Antioxidant Defences Induced by Hyperbaric Oxygen Therapy
Hyperbaric oxygen therapy (HBOT) has been proved as an important tool in healing of CO poisoning, necrosis, ischemic wounds, inflammatory diseases or brain injuries. Reactive oxygen species (ROS) play a key role in healing potential of HBOT however potential side effects must be taken into account. Equally important is also duration of HBOT. We can conclude, that despite several decades of HBOT...
متن کاملOxidative stress is fundamental to hyperbaric oxygen therapy.
The goal of this review is to outline advances addressing the role that reactive species of oxygen and nitrogen play in therapeutic mechanisms of hyperbaric oxygen. The review will be organized around major categories of problems or processes where controlled clinical trials have demonstrated clinical efficacy for hyperbaric oxygen therapy. Reactive species are now recognized to play a major ro...
متن کاملAnti-inflammatory and anti-apoptotic effects of hyperbaric oxygen preconditioning in a rat model of cisplatin-induced peripheral neuropathy
Objective(s): Cisplatin-induced peripheral neuropathy is a debilitating side effect in patients receiving this drug. Recent studies suggest hyperbaric oxygen (HBO) therapy as a new treatment approach for models of neural injury. The aim of the current study was to determine the protective effects of HBO preconditioning against peripheral neuropathy induced by Cisplati...
متن کاملThe Physiology and Pathophysiology of the Hyperbaric and Diving Environments Oxidative stress is fundamental to hyperbaric oxygen therapy
Thom SR. Oxidative stress is fundamental to hyperbaric oxygen therapy. J Appl Physiol 106: 988 –995, 2009. First published October 9, 2008; doi:10.1152/japplphysiol.91004.2008.—The goal of this review is to outline advances addressing the role that reactive species of oxygen and nitrogen play in therapeutic mechanisms of hyperbaric oxygen. The review will be organized around major categories of...
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